Publication Search
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Lau H, Laserna AKC, Li SFY. 1H NMR-based metabolomics for the discrimination of celery (Apium graveolens L. var. dulce) from different geographical origins.. Food chemistry. 2020 Dec 01; 332:127424. |
1H NMR-based metabolomics for the discrimination of celery (Apium graveolens L. var. dulce) from different geographical origins. | Celery (Apium graveolens L. var dulce) is a widely cultivated vegetable which is popularly consumed due to its nutrient content and contains bioactive metabolites with positive effects on human physiology. In this study, 1H NMR spectroscopy… |
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Tomassini A, Sciubba F, Di Cocco ME, Capuani G, Delfini M, Aureli W, Miccheli A. (1)H NMR-Based Metabolomics Reveals a Pedoclimatic Metabolic Imprinting in Ready-to-Drink Carrot Juices.. Journal of agricultural and food chemistry. 2016 Jun 29; 64… |
(1)H NMR-Based Metabolomics Reveals a Pedoclimatic Metabolic Imprinting in Ready-to-Drink Carrot Juices. | Carrots are usually consumed in their native form or processed into many different products. Carrot juice is a popular beverage consumed throughout the world and is attracting increasing attention due to its nutritional value, being a natural… |
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Driscoll, P. C. '1h nmr studies of plastocyanin in solution. Ph.D. Thesis. 1987. University of Oxford (United Kingdom). |
'1h nmr studies of plastocyanin in solution | This thesis describes the application of some modern techniques in nuclear magnetic resonance (NMR) spectroscopy to the `blue' copper redox protein plastocyanin. Two varieties of the protein, obtained from spinach and parsley leaves, with 99 and 97… | |
Garfagnoli, David Joseph. 1. SYNTHESIS OF ALPHA-ESTERS OF 1,2,3-PROPANETRICARBOXYLIC ACID. 2. GCMS ANALYSIS OF ISOMERIC OLEFINS. 3. AN OXIRANYLPHENYL ANGELATE FROM PIMPINELLA DIVERSIFOLIA (ALTERNARIA ALTERNATA, FATTY ACIDS). Ph.D. Thesis. 1984.… |
1. SYNTHESIS OF ALPHA-ESTERS OF 1,2,3-PROPANETRICARBOXYLIC ACID. 2. GCMS ANALYSIS OF ISOMERIC OLEFINS. 3. AN OXIRANYLPHENYL ANGELATE FROM PIMPINELLA DIVERSIFOLIA (ALTERNARIA ALTERNATA, FATTY ACIDS) | Methods are described for preparation of -mono-esters of 1,2,3-propanetricarboxylic acid. Oxidation of methyl cyclopent-3-ene-1-carboxylate with RuO(,4) gives 3-(methoxycarbonyl)-pentanedioic acid, which is converted readily to the corresponding… | |
Luo, Qiao Qi. (1)the proton nuclear magnetic resonance-pattern recognition research of rhodiola crendata from different districts (2)the proton nuclear magnetic resonance-pattern recognition research of angelica dahurica var. formosana from… |
(1)the proton nuclear magnetic resonance-pattern recognition research of rhodiola crendata from different districts (2)the proton nuclear magnetic resonance-pattern recognition research of angelica dahurica var. formosana from different districts | Translation from original language as provided by author This dissertation was composed of two parts. Chapter one of the first part describes The Proton Nuclear Magnetic Resonance-Pattern Recognition Research of Rhodiola crendata from Different… | |
Pszczola D. 2001: a spice odyssey. Food technology. 2001 Jan; 55(1):36-44. |
2001: a spice odyssey | ||
KOMAMINE A, MURATA N, NOMURA K. 2004 SIVB CONGRESS SYMPOSIUM PROCEEDING: MECHANISMS OF SOMATIC EMBRYOGENESIS IN CARROT SUSPENSION CULTURES –– MORPHOLOGY, PHYSIOLOGY, BIOCHEMISTRY, AND MOLECULAR BIOLOGY. In vitro cellular & developmental… |
2004 SIVB CONGRESS SYMPOSIUM PROCEEDING: MECHANISMS OF SOMATIC EMBRYOGENESIS IN CARROT SUSPENSION CULTURES –– MORPHOLOGY, PHYSIOLOGY, BIOCHEMISTRY, AND MOLECULAR BIOLOGY | Various aspects of somatic embryogenesis in carrot suspension cultures were reviewed on the basis of results obtained in our laboratory. We have established high-frequency and synchronous somatic embryogenesis systems needed for biochemical and… | |
Hwang JA, Hwang MK, Jang Y, Lee EJ, Kim JE, Oh MH, Shin DJ, Lim S, Ji Go, Oh U, Bode AM, Dong Z, Lee KW, Lee HJ. 20-O-β-d-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginseng, inhibits colon cancer growth by targeting TRPC channel-… |
20-O-β-d-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginseng, inhibits colon cancer growth by targeting TRPC channel-mediated calcium influx. | Abnormal regulation of Ca(2+) mediates tumorigenesis and Ca(2+) channels are reportedly deregulated in cancers, indicating that regulating Ca(2+) signaling in cancer cells is considered as a promising strategy to treat cancer. However, little is… |
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Lim TG, Jeon AJ, Yoon JH, Song D, Kim JE, Kwon JY, Kim JR, Kang NJ, Park JS, Yeom MH, Oh DK, Lim Y, Lee CC, Lee CY, Lee KW. 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid… |
20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes. | The aim of the present study was to determine the mechanisms through which 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD) promotes the production of hyaluronic acid (HA) in human keratinocytes. 20GPPD is the primary bioactive metabolite… |
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Kim JR, Choi J, Kim J, Kim H, Kang H, Kim EH, Chang JH, Kim YE, Choi YJ, Lee KW, Lee HJ. 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol-fortified ginseng extract attenuates the development of atopic dermatitis-like symptoms in NC/Nga mice..… |
20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol-fortified ginseng extract attenuates the development of atopic dermatitis-like symptoms in NC/Nga mice. | ETHNOPHARMACOLOGICAL RELEVANCE |
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Zhang R, Chung Y, Kim HS, Kim DH, Kim HS, Chang WY, Hyun JW. 20-O-(β-D-glucopyranosyl)-20(S)-protopanaxadiol induces apoptosis via induction of endoplasmic reticulum stress in human colon cancer cells.. Oncology reports. 2013 Apr; 29(… |
20-O-(β-D-glucopyranosyl)-20(S)-protopanaxadiol induces apoptosis via induction of endoplasmic reticulum stress in human colon cancer cells. | Previously, we reported that 20-O-(β-D-gluco-pyranosyl)-20(S)-protopanaxadiol (Compound K, a meta-bolite of ginseng saponin) induces mitochondria-dependent and caspase-dependent apoptosis in HT-29 human colon cancer cells… |
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Lee SM, Kim SC, Oh J, Kim JH, Na M. 20(R)-Ginsenoside Rf: A new ginsenoside from red ginseng extract. Phytochemistry letters. 2013; 6(4):620-624. |
20(R)-Ginsenoside Rf: A new ginsenoside from red ginseng extract | In spite of the general concept that herbal supplements are safe, there is a lack of appropriate quality control measures and regulations that often culminates in serious undesirable effects such as allergic reactions and renal and liver damage.… | |
Li WL, Li K, Chang WG, Shi H, Zhang WX, Wang Z, Li W. 20(R)-ginsenoside Rg3 alleviates diabetic retinal injury in T2DM mice by attenuating ROS-mediated ER stress through the activation of the Nrf2/HO-1 axis.. Phytomedicine : international journal… |
20(R)-ginsenoside Rg3 alleviates diabetic retinal injury in T2DM mice by attenuating ROS-mediated ER stress through the activation of the Nrf2/HO-1 axis. | BACKGROUND |
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Zhou YD, Hou JG, Liu W, Ren S, Wang YP, Zhang R, Chen C, Wang Z, Li W. 20(R)-ginsenoside Rg3, a rare saponin from red ginseng, ameliorates acetaminophen-induced hepatotoxicity by suppressing PI3K/AKT pathway-mediated inflammation and apoptosis..… |
20(R)-ginsenoside Rg3, a rare saponin from red ginseng, ameliorates acetaminophen-induced hepatotoxicity by suppressing PI3K/AKT pathway-mediated inflammation and apoptosis. | Although ginsenoside Rg3 was isolated as a major component of Korea red ginseng and confirmed to exert potential hepatoprotective effect on acetaminophen (APAP)-induced liver injury via induction of glutathione S-transferase (GST) in vitro, thein… |
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Phi LTH, Wijaya YT, Sari IN, Kim KS, Yang YG, Lee MW, Kwon HY. 20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis.. OncoTargets and therapy.… |
20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis. | Background |
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Liu J, Shiono J, Shimizu K, Yu H, Zhang C, Jin F, Kondo R. 20(R)-ginsenoside Rh2, not 20(S), is a selective osteoclastgenesis inhibitor without any cytotoxicity.. Bioorganic & medicinal chemistry letters. 2009 Jun 15; 19(12):3320-3. |
20(R)-ginsenoside Rh2, not 20(S), is a selective osteoclastgenesis inhibitor without any cytotoxicity. | Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases, and osteoclast inhibitors are the most widely used treatments for these diseases. Ginsenosides, the main component of ginseng, have been known… |
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Lv Y, Zhang Y, Feng J, Zhao T, Zhao J, Ge Y, Yang X, Han H, Zhang M, Chen L, Xu M, Guan F. (20R)-Panaxadiol as a Natural Active Component with Anti-Obesity Effects on ob/ob Mice via Modulating the Gut Microbiota.. Molecules (Basel, Switzerland).… |
(20R)-Panaxadiol as a Natural Active Component with Anti-Obesity Effects on ob/ob Mice via Modulating the Gut Microbiota. | Obesity is an important cause of diseases such as type 2 diabetes, non-alcoholic fatty liver and atherosclerosis. The use of ingredients extracted from traditional Chinese medicine for weight loss is now receiving more and more attention. Ginseng… |
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Lv Y, Lv X, Feng J, Cheng F, Yu Z, Guan F, Chen L. (20R)-panaxadiol improves obesity by promoting white fat beigeing.. Frontiers in pharmacology. 2023; 14:1071516. |
(20R)-panaxadiol improves obesity by promoting white fat beigeing. | Introduction: Obesity is an important cause of a range of metabolic diseases. However, the complex mechanisms of obesity and its related diseases make some weight loss methods ineffective or have safety issues. Ginseng, a specialty of Jilin… |
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Li Y, Luo B, Lin X, Bai D, Li L, Gao D, Li X, Zhong X, Wei Y, Yang L, Zhu X, Han L, Tian H, Zhang R, Wang P. 20(R)-Panaxatriol enhances METTL3-mediated m6A modification of STUB1 to inhibit autophagy and exert antitumor effects in Triple-Negative… |
20(R)-Panaxatriol enhances METTL3-mediated m6A modification of STUB1 to inhibit autophagy and exert antitumor effects in Triple-Negative Breast Cancer cells. | BACKGROUND |
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Wang W, Wang H, Rayburn ER, Zhao Y, Hill DL, Zhang R. 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol, a novel natural product for prostate cancer therapy: activity in vitro and in vivo and mechanisms of action.. British journal of cancer.… |
20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol, a novel natural product for prostate cancer therapy: activity in vitro and in vivo and mechanisms of action. | We recently isolated 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol (25-OCH3-PPD), a natural product from Panax notoginseng, and demonstrated its cytotoxicity against a variety of cancer cells. Here we report the effects of this compound in… |
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Kim MY, Cho JY. 20S-dihydroprotopanaxadiol, a ginsenoside derivative, boosts innate immune responses of monocytes and macrophages.. Journal of ginseng research. 2013 Jul; 37(3):293-9. |
20S-dihydroprotopanaxadiol, a ginsenoside derivative, boosts innate immune responses of monocytes and macrophages. | 20S-dihydroprotopanaxadiol (2H-PPD) is a derivative of protopanaxadiol, a glycone of ginsenosides prepared from Panax ginseng. Although ginsenosides and acidic polysaccharides are known to be major active ingredients in ginseng, the… |
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Kim MY, Cho JY. 20S-dihydroprotopanaxatriol modulates functional activation of monocytes and macrophages.. Journal of ginseng research. 2013 Jul; 37(3):300-7. |
20S-dihydroprotopanaxatriol modulates functional activation of monocytes and macrophages. | 20S-dihydroprotopanaxatriol (2H-PPT) is a derivative of protopanaxatrol from ginseng. Unlike other components from Panax ginseng, the pharmacological activity of this compound has not been fully elucidated. In this study, we investigated the… |
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Kim J, Dan KB, Kim KU, Min H. 20(S)-ginsenoside Rg3 alleviates DSS-induced colitis by promoting ERK-dependent maturation of MDSCs into M2 macrophages.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2025 Jan; 182:117789… |
20(S)-ginsenoside Rg3 alleviates DSS-induced colitis by promoting ERK-dependent maturation of MDSCs into M2 macrophages. | Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells with immunosuppressive functions that play various roles in tumors and inflammatory diseases. In colitis, MDSCs accumulate in the inflamed colon, where they mature into M2-… |
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Tian J, Zhang S, Li G, Liu Z, Xu B. 20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain.. Phytotherapy research : PTR. 2009 Apr; 23(4):486-91. |
20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain. | Ginseng, the root of Panax ginseng C.A. Meyer (Araliaceae), is a well-known traditional Chinese herbal medicine. Ginsenosides, which are triterpene derivatives that contain sugar moieties, are the main active ingredients of ginseng. 20(S)-… |
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Park MW, Ha J, Chung SH. 20(S)-ginsenoside Rg3 enhances glucose-stimulated insulin secretion and activates AMPK.. Biological & pharmaceutical bulletin. 2008 Apr; 31(4):748-51. |
20(S)-ginsenoside Rg3 enhances glucose-stimulated insulin secretion and activates AMPK. | Although Panax ginseng has been widely used in oriental countries for pharmacological effects such as anti-diabetic, anti-inflammatory, adaptogenic and anti-fatigue activities, the active ingredient is not yet fully identified. In our preliminary… |